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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4350 | Palifosfamide | ZIO-201,Isophosphamide mustard,Isophosphoramide mustard | DNA Alkylator/Crosslinker , DNA Alkylation , Drug Metabolite |
Palifosfamide (Isophosphamide mustard) lysine (ZIO-201) is a stable form of palifosfamide. Palifosfamide lysine has broad activity in sarcoma lines in vitro. The IC50 ranges from 2.25 to 6.75 μM for most cell lines excep... | |||
T71500 | Palifosfamide tromethamine | IPM tromethamine,Isophosphoramide mustard tromethamine,ZIO-201 tromethamine,Isophosphoramide mustard tromethamine ; IPM tromethamine ; ZIO-201 tromethamine | |
Palifosfamide (tromethamine), a synthetically derived alkylating agent, exhibits potential antineoplastic properties. Acting as the stabilized active metabolite of ifosfamide, it irreversibly alkylates and crosslinks DNA... | |||
T71498 | FLB-457 | ||
FLB-457 is a dopamine antagonist. | |||
T3615 | Evofosfamide | TH-302 | Apoptosis , Others |
Evofosfamide (TH-302) is a hypoxia-activated prodrug of the cytotoxin bromo-isophosphoramide mustard (Br-IPM) conjugated with 2-nitroimidazole, with potential antineoplastic activity. When exposed to hypoxic conditions, ... |